In 2026, IBI-Ag completed the proof-of-concept for what we believe is the world’s first AI-driven de novo protein design platform built specifically for bioinsecticide discovery.
Unlike approaches that screen existing biological libraries or modify known proteins, de novo design uses computational AI to create entirely new protein structures — engineered from first principles to bind target proteins with desired properties.
The Platform in Brief
The IBI-Ag AI De Novo Platform integrates:
Proprietary target data
A curated bank of insect protein targets validated for pest control relevance, including both soluble and membranal proteins
AI-driven structural design
Advanced computational models that generate novel protein binders optimized for affinity, specificity, stability solubility and more
Biophysical property calculation
Automated in silico assessment of candidate proteins across multiple functional parameters
Lab-in-the-Loop validation
Iterative experimental testing that feeds data back into the computational pipeline, continuously improving design accuracy
Intellectual Property
IBI-Ag’s technology is protected by a growing portfolio of intellectual property, including target data, modes of action and protein libraries